Arthur Penhaligon has terrible, dangerous asthma. He has to keep an inhaler with him at all times, and has been warned to not engage in physical that will make him breathe too hard. However, on his first day at a new school, the gym teacher yells at him for not keeping up with the rest of the class during a run. He tries, and collapses when his throat begins to close! Arthur is sure he is going to die and experiences a dream or hallucination in which an old, stooped man is pushing a young, handsome man in a wheelchair. The handsome man hangs Arthur a key fashioned to look like the minute hand on an antique clock, and tells him it will help him breathe. When Arthur comes to after this strange dream, he is still clutching the key, a mysterious locked book, and is now able to control his breathing. Weirder things begin to happen… a plague seems to be spreading, and Arthur is being hunted by men with the faces of dogs and blood-covered wings who want the key he was given back. They have been sent by the dark Mister Monday who still has the Hour Hand key and needs the Minute Hand key back in order to keep ruling a mysterious old house that might contain a universe within itself… Can Arthur, along with his two best friends, steal the other key from Mister Monday and save the universe? This exciting book for fans of Harry Potter will keep you guessing until the very end!